sta-21 (ochromycinone) Search Results


20mg body weight kg sta 21 mce hy 18061  (MedChemExpress)
92
MedChemExpress 20mg body weight kg sta 21 mce hy 18061
20mg Body Weight Kg Sta 21 Mce Hy 18061, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sta-21+(ochromycinone)/Ochromycinone/pmc09951332__ADVS___10___2206335___s001-186-64-68
Average 92 stars, based on 1 article reviews
20mg body weight kg sta 21 mce hy 18061 - by Bioz Stars, 2026-10
92/100 stars
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sta21  (MedChemExpress)
90
MedChemExpress sta21
Effects of a NF-κB inhibitor on the levels of p-NF-κB and <t>p-STAT3</t> and on the levels of secreted IL-6, IL-8, Rantes and MCP-1 in HcH, MΦ cultures or in HcH/MΦ coculture. ( A ) Effect of a NF-κB inhibitor on the level of p-NF-κB (Western blot) and on the levels (ELISA) of IL-6, IL-8, Rantes, MCP-1 in HcH cultures and the effect of IL-1β treatment. Representative data from one of three experiments are shown; ( B ) Levels of p-STAT3 were determined by Western blotting) and the levels of IL-6 and IL-8 were determined by ELISA assay, in MΦ cultures. Effect of treatment with IL-1β, IL-6, aIL-6 or <t>STA21.</t> Co, control. Representative data from one of three experiments are shown; ( C ) Expression of p-STAT3 (Western blotting) and on the level (ELISA) of IL-6, IL-8, Rantes, MCP-1 in MΦ cocultures. Effect of IL-1β and NF-κB inhibitor. β-Tubulin: protein loading control, Pg/mL: picogram/mL. Representative data from one of three experiments are shown.
Sta21, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sta-21+(ochromycinone)/(%2B)-Ochromycinone/pmc04882693-70-64-69
Average 90 stars, based on 1 article reviews
sta21 - by Bioz Stars, 2026-10
90/100 stars
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sta-21 (ochromycinone)  (Aladdin Scientific Corporation)
N/A
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
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ochromycinone (sta-21)  (Aladdin Scientific Corporation)
N/A
Application：STA-21 has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor to study its effects on glioblastoma and primary glioblastoma cells. It has also been used as a STAT3 dimerization inhibitor
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Effects of a NF-κB inhibitor on the levels of p-NF-κB and p-STAT3 and on the levels of secreted IL-6, IL-8, Rantes and MCP-1 in HcH, MΦ cultures or in HcH/MΦ coculture. ( A ) Effect of a NF-κB inhibitor on the level of p-NF-κB (Western blot) and on the levels (ELISA) of IL-6, IL-8, Rantes, MCP-1 in HcH cultures and the effect of IL-1β treatment. Representative data from one of three experiments are shown; ( B ) Levels of p-STAT3 were determined by Western blotting) and the levels of IL-6 and IL-8 were determined by ELISA assay, in MΦ cultures. Effect of treatment with IL-1β, IL-6, aIL-6 or STA21. Co, control. Representative data from one of three experiments are shown; ( C ) Expression of p-STAT3 (Western blotting) and on the level (ELISA) of IL-6, IL-8, Rantes, MCP-1 in MΦ cocultures. Effect of IL-1β and NF-κB inhibitor. β-Tubulin: protein loading control, Pg/mL: picogram/mL. Representative data from one of three experiments are shown.

Journal: Nutrients

Article Title: Resveratrol Interferes with IL1-β-Induced Pro-Inflammatory Paracrine Interaction between Primary Chondrocytes and Macrophages

doi: 10.3390/nu8050280

Figure Lengend Snippet: Effects of a NF-κB inhibitor on the levels of p-NF-κB and p-STAT3 and on the levels of secreted IL-6, IL-8, Rantes and MCP-1 in HcH, MΦ cultures or in HcH/MΦ coculture. ( A ) Effect of a NF-κB inhibitor on the level of p-NF-κB (Western blot) and on the levels (ELISA) of IL-6, IL-8, Rantes, MCP-1 in HcH cultures and the effect of IL-1β treatment. Representative data from one of three experiments are shown; ( B ) Levels of p-STAT3 were determined by Western blotting) and the levels of IL-6 and IL-8 were determined by ELISA assay, in MΦ cultures. Effect of treatment with IL-1β, IL-6, aIL-6 or STA21. Co, control. Representative data from one of three experiments are shown; ( C ) Expression of p-STAT3 (Western blotting) and on the level (ELISA) of IL-6, IL-8, Rantes, MCP-1 in MΦ cocultures. Effect of IL-1β and NF-κB inhibitor. β-Tubulin: protein loading control, Pg/mL: picogram/mL. Representative data from one of three experiments are shown.

Article Snippet: The crucial role of IL-6 in our model was evaluated by using anti-IL-6 (from Merck Chimie SAS 201, Rue Carnot, Fontenay sous Bois, Île-de-France 94126, France), p65 antibody S536 (anti p-NF-κB) and Y705 (anti p-STAT3 antibody) (from Abcam, 24 rue Louis Blanc, 75010 PARIS, France), the NF-κB phosphorylation inhibitors (BAY-11-7082) (from Merck Chimie SAS, 201, Rue Carnot, Fontenay sous Bois, Île-de-France 94126, France), and STA21 (STAT3 phosphorylation inhibitor) (from Medchemexpress Europe Box 128-521-1298 Stockholm, Sweden).

Techniques: Western Blot, Enzyme-linked Immunosorbent Assay, Control, Expressing